Aspergillosis of the lungs: causes, treatment

The cause of the disease aspergillosis of the lungs is the involvement of the bronchopulmonary system with mold fungi.

Aspergillus is found in soil, air, sulfur springs, water. Aspergillus sources include books, pillows, showers, ventilation systems, air humidifiers, indoor plants, food, hay. In the premises, the concentration of aspergilli in the rows exceeds their content in the open air.

A large number of aspergillus spores occur in the USA, western Europe, and Asia. Moreover, the inhabitants of rural areas are sick many times more often than adherents of city life. The disease is not transmitted from a sick person to a healthy person.

Risk group

Often, aspergillosis lungs workers grinders and pigeons, as pigeons quite often suffer from this disease. People with diabetes are at risk because they are most susceptible to a disease such as pulmonary aspergillosis who are still at risk:

  • people of advanced age,

  • HIV-infected,

  • people suffering from chronic diseases of the lungs and the cardiovascular system,

  • patients who underwent organ transplantation,

  • people with impaired functions of the endocrine system,

  • workers of farms, weaving industries, vegetable warehouses, wood processing shops, agronomists, hunters.

  • Forecast

    In the absence of necessary treatment, the prognosis of the disease is very unfavorable. The risk of death is very high, especially in the generalized form of pulmonary aspergillosis.

    Causes of pulmonary aspergillosis

    The fungus spores enter the body by inhaling contaminated air or through the skin, however, as already mentioned, infection of a healthy person from a sick person is not possible.

    When inhaling, the spores of the fungus penetrate into the bronchi and lungs, after which the fungus multiplies rapidly. There is a lesion of the pleura, lymph nodes, and thanks to the current of the blood, the fungus easily spreads throughout the human body, hitting internal organs.

    Treatment of pulmonary aspergillosis

    There are three methods of treating the disease:

  • This isotropic

  • Symptomatic therapy

  • Surgical

  • For mild and moderate forms of pulmonary aspergillosis, etiotropic treatment is used, which includes the administration of itraconazole (200-400 mg per day for 1 admission for 4-6 months), ketoconazole (800 mg per day for 1 admission for 4-6 months). The severe form of pulmonary aspergillosis involves intravenous administration of amphotericin B preparations, the dosage is calculated based on 1 ml /kg. Introduction every other day.

    Symptomatic therapy involves the use of antipyretic, analgesic, antihistamine, antibacterial, anticonvulsant, diuretic, antiseptic drugs, glucocorticosteroids, vitamins.

    Surgical treatment is the drainage of the cavity of the pleura in the defeat of the lungs, pleura. In the event that the infection occupies 1-2 lobes of the lung, lobectomy, that is, removal of the lobe of the lung, can be performed.