The issue of artificial birth and the stimulation of childbirth is not an easy one, and it can be said for a long time about it: both on the moral and ethical side of this issue, and on the physical features and physiological consequences.
In this article we will not touch these parties, but consider those drugs that are used for artificial birth.
Principle of action of drugs for artificial delivery
For starters, we will voice one important rule: use of drugs to stimulate labor can not be categorically impossible, because even in a hospital, artificial birth results in serious complications, and at home without medical supervision it is simply dangerous.
The physiological mechanisms that function during pregnancy are aimed at suppressing the contraction of the smooth muscles of the uterus to prevent miscarriage. A substance that struggles with contractions of the uterine muscles is the sex female hormone progesterone. In the event that it is not enough, there is a risk of spontaneous miscarriage.
To induce muscular contraction of the uterus, that is, to stimulate artificial delivery, drugs that suppress the action of progesterone and other hormonal drugs are used. These are Mifepristone, Oxytocin and Prostaglandins.
Medicines for artificial childbirth
Oxytocin Is the hormone of the posterior lobe of the pituitary gland. The pituitary gland is responsible for the contraction of the uterus musculature and the secretion of human milk. The birth is caused precisely by this stimulation of uterine contractions. Oxytocin is injected intravenously with 5% glucose solution. Gradually increase the dose, and labor activity also increases, as a result of which artificial birth begins.
Oxytocin has contraindications: this position of the fetus is a transverse or oblique, narrow pelvis of the woman in childbirth, the threat of rupture of the uterus, scars on the uterus.
Prostalandiny Are derived from polyunsaturated fatty acids, biologically active substances. Prostalandins also stimulate contractions in the musculature of the uterus. Preparations containing prostaglandins of type E, reduce the tone of the nonpregnant uterus, its motor activity and strengthen them during pregnancy. Other preparations of prostaglandins of type F have an abortive effect.
Contraindications to the use of prostalandins: infectious and inflammatory diseases, diseases of the respiratory system, cardiovascular system, liver and kidneys.
Mifepristone - an antagonist of the female sex hormone progesterone, which does not allow to carry out its work progesterone to prevent contractions of uterine muscles. The drug is able to destroy the small blood vessels and the mucous membrane of the uterus, because of which the mucosa is rejected; The drug also increases the concentration of prostaglandins that contribute to uterine contraction. As a result begins labor activity, the cervix is opened, the fetus is removed from the uterus. Mifepristone is sometimes used together with prostalinands to enhance the effect.