D-dimer in pregnancy. What are the norms of

Pregnancy is full not only of new sensations, emotions, expectations, but also frequent trips to the polyclinic. From the first visit to the women's consultation, you must take all kinds of tests, sometimes - incomprehensible. One such assay is the analysis for d-dimer in pregnancy. It can not be underestimated, it is really very important. Pregnancy makes its own adjustments to the activities of every system of the woman's body.

Everyone knows hormonal changes in the female body. I would like to note the increase in the level of estrogen - this hormone is responsible for blood clotting during pregnancy.

If the walls of the vessels are damaged, that is, bleeding occurs, fibrinogen takes the form of fibrin, settling on the area of ​​damage, forms a network into which blood cells enter, strengthening the network - a blood clot is formed, that is, a thrombus. It is the thrombus that closes the lesions, preventing bleeding. The healing process causes fibrinolysis, that is, the decomposition of the thrombus into fragments, one of which is the d-dimer.

The analysis for d-dimers is given to all future mothers in order to determine the risk of formation of blood clots. To carry out the analysis, a woman takes blood from a vein, and for twelve hours before taking the material, one should neither drink nor eat.

Norms of pregnancy

D-dimer in the absence of pregnancy, as well as in men is not more than 500ng /ml. When pregnancy, the level of d-dimer depends on the period of pregnancy. In the first trimester the maximum concentration of the d-dimer is 750 ng /ml, in the second - 1000 ng /ml, in the third the norm of the dimer can be up to 1500 ng /ml.

If you suffer from diseases of the hemostatic system, such as thrombophilia, varicose veins, thrombosis, it may be necessary to take an assay for d-dimer several times during pregnancy. Thrombi occur not only when the vessels and tissues are damaged, blood clots can also form inside the vessels.

When an assay is scheduled for d-dimer in pregnancy?

Analysis for d-dimer in pregnancy is prescribed with symptoms of thrombosis, suspicion of pulmonary embolism, DVS. Some increase in the level of d-dimer can be observed in the postoperative period, with injuries, diseases of the cardiovascular system, oncology, liver diseases, in old age.

Elevated indices of d-dimer indicate the presence of blood clotting problems in a future mother. Often this happens with diabetes, against kidney and liver diseases, gestosis, with infectious diseases, premature detachment of the placenta.

High d-dimer contributes to the occurrence of dangerous complications, such as:

  • Detachment of the placenta.

  • Miscarriage.

  • Premature birth.

  • It is very important that a pregnant woman with a high level of d-dimer is under the control of doctors. As we have already explained, an elevated level of d-dimer in pregnancy is the most dangerous condition that requires hospitalization.


    If the d-dimer is elevated in pregnancy, then drugs such as fractiparin and reopolyglucin are used for treatment. As an additional therapy, actovegin and curantyl can be used.

    Reduced d-dimer in pregnancy

    In future mothers, the d-dimer index increases significantly, so low thresholds for the d-dimer level are not given. Low d-dimer does not entail serious complications, so medical workers do not attach importance to it.

    However, there are cases when, in pregnancy, the level of d-dimer is below the norms not for pregnant women and men, that is less than 500 ng /ml, there is reason to speak about serious violations of blood coagulability. This can cause severe bleeding during labor, which in turn is a risk of death. Therefore it is very important to undergo examination and treatment.