Eosinophils in adults: the reasons for the increase

Eosinophils called specific white blood cells. These blood cells perform a number of important functions. One of them is the provision of stable immunity, which is due to their cytotoxic properties. Eosinophils in adults can be increased - this phenomenon is called eosinophilia.

Characteristics of eosinophils

Blood cells of eosinophils are characterized by amoeboid movement. They can easily penetrate the walls of the vessels - this is one of their most important properties. Another important property is chemotaxis, which means that they can actively move in the direction of the inflammation focus and areas of damaged tissue. Eosinophils are microphages, that is, they are capable of absorbing foreign particles of the smallest size.

Eosinophils are distinguished by the ability to release or, on the contrary, actively bind the substances released during the inflammation or allergic reaction, including histamine and some others. The number of eosinophils in the blood can increase. This is due to a variety of reasons why this can happen. In an adult, the number of eosinophils is normal at 120-350 units per m /l of blood. Deviation from the norm indicates a problem.

What is the reason for increasing the level of eosinophils?

The main feature of eosinophils, which was mentioned above, is the ease of release and binding of histamine substance. And an increase in the level of histamine, in turn, entails the appearance of the main symptoms of allergy. That is why, in a number of reasons for increasing the level of eosinophils, one should first of all speak of an allergic reaction. The consequence of increased histamine is the appearance of rash, swelling of the mucous membranes.

Eosinophils as a variety of white blood cells have the ability and suspend, and trigger the mechanism of the onset and development of an allergic reaction. Here you can also include:

  • bronchial asthma;

  • also allergic rhinitis (runny nose);

  • hay fever;

  • hypersensitive susceptibility to the components of various drugs;

  • atopic dermatitis.

  • Elevated levels of eosinophils may also indicate the presence of any parasitic disease . This is due to the fact that one of the functions of these white blood cells is the maintenance of antiparasitic immunity. In connection with this, it is natural that eosinophilia develops against the background of malaria, trichinosis, ascariasis, opisthorchiasis, giardiasis, etc.

    The processes associated with lead to an increase in the number of eosinophils. with the formation and growth of the tumor . These include erythremia, leukemia and some other tumor processes.

    Also, enough eosinophilia is observed for infectious diseases .

    On the formula of blood, is also often affected. problems with the functioning of the immune system, since a very important part of the defense forces are granulocytes.

    The development of eosinophilia is also led by connective tissue lesions (for example, rheumatoid arthritis), heart defects.

    The use of certain medicinal preparations can also cause an increase in the level of eosinophils. These are preparations containing beta-blockers, sex hormones, penicillin, sulfonamides, chemotrypsin, etc.

    From the above it follows that the level of eosinophils may increase under the influence of different factors, and for the establishment of an accurate diagnosis it is necessary to carry out certain analyzes and studies.